Extrusion–spheronization a promising pelletization technique: In-depth review
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منابع مشابه
Pelletization Technique in Drug Delivery System- a Review
In present times, the pelletization technologies are giving much attention as they represent an efficient pathway for manufacture of new drug delivery system .It has good advantage over the conventional dosage form. Pelletization technique help in the formation of spherical beads or pellets having a diameter 0.5 -1.5 mm which can be eventually coated for preparation of modified release dosage f...
متن کاملPelletization Techniques: A Review
Pelletization is an agglomeration process that converts fine powders or granules of bulk drugs and excipients into small, free flowing, spherical or semi-spherical units, referred to as pellets. This review outlines manufacturing of spherical pellets. The manufacturing techniques include Drug layering, Extrusion-Spheronization, Cryopelletization, Compression, Balling, Hot-Melt Extrusion Technol...
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Pelletization process first came into existence way back during the 1950s, when the first product was introduced to the market. These pelletized dosage forms have gained popularity considerably from then because of their distinct advantages, such as ease of capsule filling because of better flow properties of the perfectly spherical pellets; enhancement of drug dissolution; ease of coating; sus...
متن کاملA Novel Freeze Pelletization Technique for Preparing Matrix Pellets
98 Pharmaceutical Technology OCTOBER 2004 Sreekhar Cheboyina is a PhD student in the department of pharmaceutics, School of Pharmacy, University of Mississippi. Walter G. Chambliss, PhD, is director of technology management and a research professor at the Research Institute of Pharmaceutical Sciences, and professor of pharmaceutics, University of Mississippi. Christy M. Wyandt, PhD, is associat...
متن کاملCODEN : IJPNL 6 Multi unit drug delivery system – A brief review of pelletization technique
At present time pharmaceutical research and development showing its interest on drug delivery. Which enhances therapeutic action while minimizing side effect. Use of multi-particulate is the gift of that research which achieve delayed or controlled release with low risk of dose dumping, flexibility of blending to attain different release pattern as well as reproducible and short gastric residen...
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ژورنال
عنوان ژورنال: Asian Journal of Pharmaceutical Sciences
سال: 2016
ISSN: 1818-0876
DOI: 10.1016/j.ajps.2016.08.001